Which statement is part of the diagnostic criteria for steroid-responsive enteropathy?

Which statement is part of the diagnostic criteria for steroid-responsive enteropathy?

• A. Positive response to immunosuppressive therapy
• B. Positive response to dietary trial
• C. Onset within 24 hours
• D. Presence of intestinal ulcers on endoscopy

Answer: (A)

Steroid-responsive enteropathy is identified by a positive clinical response to immunosuppressive therapy, typically corticosteroids. When a patient with chronic GI signs improves markedly after starting steroids, this therapeutic response supports the diagnosis, since the condition tends to respond to immune-modulating treatment. This criterion is about how the disease behaves under treatment, not about dietary trials, rapid onset, or endoscopic findings. A dietary trial points to food-responsive enteropathy, rapid onset within 24 hours isn’t a diagnostic marker, and the presence of intestinal ulcers on endoscopy isn’t required or specific for this diagnosis.

Steroid-responsive enteropathy is identified by a positive clinical response to immunosuppressive therapy, typically corticosteroids. When a patient with chronic GI signs improves markedly after starting steroids, this therapeutic response supports the diagnosis, since the condition tends to respond to immune-modulating treatment. This criterion is about how the disease behaves under treatment, not about dietary trials, rapid onset, or endoscopic findings. A dietary trial points to food-responsive enteropathy, rapid onset within 24 hours isn’t a diagnostic marker, and the presence of intestinal ulcers on endoscopy isn’t required or specific for this diagnosis.